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Deputy Director of the ICGM

I. By the way

Courses & Training Teachings & Responsibilities Courses & Training

• 2020-present: Professor at ENSCM
• 2009-present: Charles Gerhardt Montpellier Institute
• 2003-2020: Professor at the University of Nîmes
• 1994-2003: Lecturer then Professor at the University of Technology of Compiègne
• 1989-1994: Associate Professor at the University of Technology of Compiègne
• 1987-1989: Temporary Normalien Assistant at the University of Technology of Compiègne
• 1985-1987: Massachusetts Institute of Technology. Cambridge U.S.A (A.M. Klibanov lab).
• 1984: Aggregation in Biochemistry, Biological Engineering. ENS Paris-Saclay

Teachings & Responsibilities

Teachings

• ENSCM: Practical Work in Analytical Chemistry, Practical Work in Biotechnology, Life Metabolic Chemistry and Structure and Functions of Proteins
• Master in Biology and Health, University of Montpellier: Nanotechnologies and multifunctional systems for therapeutic and diagnostic purposes

Responsibilities

• Head of the Chemistry Biology Health Option at ENSCM
• Co-leader of the Translational Medicinal Chemistry course of the Master in Biology and Health

Ii. Research activities

A biomimetic system designed for protein translocation studies

A biomimetic membrane model consists in a tethered lipid bilayer (tBLM) that is assembled on an amine-gold surface derivatized with calmodulin (CaM). The assembled bilayer forms a continuous and protein-impermeable boundary completely separating the underlying calmodulin (trans side)from the medium above (cis side).The overal process is monitored by surface plasmon resonance (SPR) spectroscopy

Research themes Collaborations & Contracts Research themes

• Biomimetic membranes
  • Model protein/membrane interactions
  • Model nanoparticle/membrane interactions

• Molecular interaction measurements
  • Surface plasmon resonance
  • Quartz microbalance with dissipation measurement

Collaborations & Contracts

• Dr Daniel Ladant and Dr Alexandre Chenal, Institut Pasteur, Paris
• Prof Wolfgang Knoll, Dr Jakob Andersson, AIT, Vienna.

Iii. Scientific production