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Taillefer Research Group

The team (Molecular Synthesis Methodology) is composed by around 12 members with 4 permanent researchers:

  • Marc Taillefer (DR CNRS / Head of the team): see below
  • Florian Monnier (Pr ENSCM): see hyperlink
  • Florian Jaroschick (CR CNRS): see hyperlink
  • Alexis Prieto (CR CNRS): see hyperlink

Marc Taillefer biography

Marc Taillefer studied chemistry and earned his Ph.D. from the University Paul Sabatier, Toulouse, France, under the supervision of Dr Jean-Jacques Brunet in 1989. He was then a postdoc at the Technische Universität München, Germany, with Pr Wolfgang A. Herrmann. He became a CNRS researcher at the Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM) in 1992 and CNRS Research Director in 2004.

His research focuses on the discovery of breakthrough methodologies in the field of organic synthesis and homogeneous catalysis (C–C and C-Heteroatom bond formation via copper-, iron- and manganese- catalyzed arylation of nucleophiles, transition metal free mediated coupling reaction, and functionalization of unsaturated compounds), as well as phosphorus chemistry (synthesis, reactivity, and applications of ylides).

Among many other commitments, Marc Taillefer was President of the French Chemical Society's Organic Chemistry Division from 2012 to 2015 and, from 2018 to 2021, he was the President of the French Chemical Society (SCF).

For his pioneering work on copper catalyzed arylation couplings and their worldwide academic and industrial impact, Marc Taillefer was awarded the prestigious "Grand Prix Emile Jungfleisch" of the French Academy of Sciences in 2017, and "European Sustainable Chemistry Award" of the EuChemS in 2012, among other awards and honors.

I. By the way

Teachings & Responsabilities Professionally training Teachings & Responsabilities

  • 1999 – 2023: Head of the Molecular Synthesis Methodologies team.
  • 2018 – 2021: President of the French Chemical Society (SCF).
  • 2016 – 2021: Head of the AM2N Team: Molecular Architectures & Nanostructured Materials.
  • 2018 – 2021: Publication Director of the Actualité Chimie.
  • 2017 – 2022: École Nationale Supérieure de Chimie de Paris: Member of the Scientific Council.
  • 2012 – 2015: Chairman of the Organic Chemistry Division of the French Chemical Society (SCF).
  • 2009 – 2015: Vice President of the French Chemical Society (SCF).
  • 2004 – 2008: ENSC Montpellier: Member of the Scientific Council.
  • 2001 – 2004: ENSC Montpellier: Member of the Board of Directors

Professional training

  • 2004 – present: Research Director at CNRS.
  • 2004: Habilitation to supervise research (HDR), University Montpellier II.
  • 1992 – 2001: Researcher at CNRS.
  • 1990 – 1992: Post-Doc: Technische Universität München – Prof. W. Has. Herrmann. / Rhenium complexes.
  • 1987 – 1989: PhD: University Paul Sabatier Toulouse – Prof. I. Tkachenko & Dr. J.J Brunet. Fe catalyzed arylation & carbonylation of nucleophiles.
Ii. Research Activities

Research topics Collaborations & Contracts Research topics

Main Topics of the Team

a) Formation of C-C and C-Heteroatom bonds (C-N, C-O, C-F, C-S, C-P, C-X…) :

  • Via copper, iron, manganese or nickel based-catalytic systems.
  • In the presence of organic reductants (transition metal free conditions).
  • Via the generation of radical species in situ generated under light irradiation (photochemistry).

Arylation of nucleophiles, C-H activation, reduction, hydrofunctionalization of unsaturated compounds, alkylation…

b) New organic and organometallic transformations based on lanthanides (C-F and C-P bond activation).

(c) New phosphorus ylides: synthesis, applications in organic synthesis, coordination chemistry and catalysis.


Transversal Topics

(a) Mechanistic studies.

b) Industrial applications in homogeneous catalysis (drugs and agrochemical) & in phosphorus chemistry (crop biocontrol).

Patents – exploitation licenses – production of active ingredients – marketing of drugs in pharmacies

c) Our academic & industrial work are in the field of sustainable chemistry (low pollution, low toxicity, economically competitive).


Collaborations & Contracts

Institutional Funding of the team (since 2010)


Institutional Funding of the team (since 2010)



Iii. Scientific Production